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1

Improved long-term protection against Mycobacterium tuberculosis Beijing/W in mice after intra-dermal inoculation of recombinant BCG expressing latency associated antigens

Stephen T. Reece, Ali Nasser-Eddine, Jes Dietrich, Maik Stein, Ulrike Zedler, Sandra Schommer-Leitner, Tom H.M. Ottenhoff, Peter Andersen, Stefan H.E. Kaufmann

Journal:

Year:

2011

Language:

english

File:

PDF, 901 KB

english, 2011

2

Mycobacterium bovis BCG Vaccination Induces Divergent Proinflammatory or Regulatory T Cell Responses in Adults

Boer, Mardi C., Prins, Corine, van Meijgaarden, Krista E., van Dissel, Jaap T., Ottenhoff, Tom H. M., Joosten, Simone A., Pascual, D. W.

Journal:

Clinical and Vaccine Immunology

Year:

2015

Language:

english

File:

PDF, 5.28 MB

english, 2015

3

Mycobacterium tuberculosis Beijing Genotype Is an Independent Risk Factor for Tuberculosis Treatment Failure in Indonesia

Parwati, Ida, Alisjahbana, Bachti, Apriani, Lika, Soetikno, Rista D., Ottenhoff, Tom H., van der Zanden, Adri G. M., van der Meer, Jos, van Soolingen, Dick, van Crevel, Reinout

Journal:

The Journal of Infectious Diseases

Year:

2010

Language:

english

File:

PDF, 244 KB

english, 2010

4

Focused human gene expression profiling using dual-color reverse transcriptase multiplex ligation-dependent probe amplification (dcRT-MLPA)

Haks, Mariëlle C., Goeman, Jelle J., Magis-Escurra, Cecile, Ottenhoff, Tom H.M.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.38 MB

english, 2015

5

Genome wide approaches discover novel Mycobacterium tuberculosis antigens as correlates of infection, disease, immunity and targets for vaccination

Coppola, Mariateresa, Ottenhoff, Tom HM

Journal:

Seminars in Immunology

Year:

2018

Language:

english

File:

PDF, 554 KB

english, 2018

6

Effectiveness of Stress-Reducing Interventions on the Response to Challenges to the Immune System: A Meta-Analytic Review

Schakel, Lemmy, Veldhuijzen, Dieuwke S., Crompvoets, Paige I., Bosch, Jos A., Cohen, Sheldon, van Middendorp, Henriët, Joosten, Simone A., Ottenhoff, Tom H.M., Visser, Leo G., Evers, Andrea W.M.

Journal:

Psychotherapy and Psychosomatics

Year:

2019

Language:

english

File:

PDF, 165 KB

english, 2019

7

Development of an AAV5-based gene therapy for Fabry disease

Liu, Ying Poi, Liefhebber, Jolanda M.P., van der Zon, Tom, Paerels, Lieke, Ferraz, Maria J., Ottenhoff, Roelof, Zancanella, Vanessa, Au, Betty, Kuo, Chi-Lin, de Vries, Carlie J.M., Evers, Melvin M., K

Journal:

Molecular Genetics and Metabolism

Year:

2020

File:

PDF, 333 KB

2020

8

Natural T-helper immunity against human papillomavirus type 16 (hpv16) e7–derived peptide epitopes in patients with hpv16-positive cervical lesions: Identification of 3 human leukocyte antigen class ii–restricted epitopes

Sjoerd H. van der Burg, Maaike E. Ressing, Kitty M.C. Kwappenberg, Annemieke de Jong, Karin Straathof, Joan de Jong, Annemieke Geluk, Krista E. van Meijgaarden, Kees L.M.C. Franken, Tom H.M. Ottenhoff

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 157 KB

english, 2001

9

Quantitative and qualitative differences in HLA-DR molecules correlated with antigen-presentation capacity

Ronald Bontrop, Tom Ottenhoff, Rob Van Miltenburg, Diënne Elferink, René De Vries, Marius Giphart

Journal:

European Journal of Immunology

Year:

1986

Language:

english

File:

PDF, 731 KB

english, 1986

10

T90/44 (9.3 antigen). A cell surface molecule with a function in human T cell activation

Werner Lesslauer, Frits Koning, Tom Ottenhoff, Marius Giphart, Els Goulmy, Jon J. Van Rood

Journal:

European Journal of Immunology

Year:

1986

Language:

english

File:

PDF, 894 KB

english, 1986

11

T cell epitopes on the 36K and 65K Mycobacterium leprae antigens defined by human T cell clones

Wim C. A.Van Schooten, Tom H. M. Ottenhoff, Paul R. Klatser, Jelle Thole, René R. P.De Vries, Arend H. J. Kolk

Journal:

European Journal of Immunology

Year:

1988

Language:

english

File:

PDF, 641 KB

english, 1988

12

T cell responses to fractionated Mycobacterium leprae antigens in leprosy. The lepromatous nonresponder defect can be overcome in vitro by stimulation with fractionated M. leprae components

Tom H. M. Ottenhoff, Paul J. Converse, Negussie Gebre, Assefa Wondimu, John P. Ehrenberg, Rolf Kiessling

Journal:

European Journal of Immunology

Year:

1989

Language:

english

File:

PDF, 772 KB

english, 1989

13

Induction of antigen-specific CD4+ HLA-DR-restricted cytotoxic T lymphocytes as well as nonspecific nonrestricted killer cells by the recombinant mycobacterial 65-kDa heat-shock protein

Birhane Kale Ab, Rolf Kiessling, Jan D. A. Van Embden, Jelle E. R. Thole, Dinakantha S. Kumararatne, Pavel Pisa, Assefa Wondimu, Tom H. M. Ottenhoff

Journal:

European Journal of Immunology

Year:

1990

Language:

english

File:

PDF, 885 KB

english, 1990

14

Human suppressor T cell clones lack CD28

Shu Guang Li, Tom H. M. Ottenhoff, Peter van den Elsen, Frits Koning, Li Zhang, Tak Mak, René R. P. De Vries

Journal:

European Journal of Immunology

Year:

1990

Language:

english

File:

PDF, 760 KB

english, 1990

15

HLA-DQ molecules and the control of Mycobacterium leprae-specific T cell nonresponsiveness in lepromatous leprosy patients

Tom H. M. Ottenhoff, Charlotte Walford, Yasuharu Nishimura, N. B. B. Reddy, Takehiko Sasazuki

Journal:

European Journal of Immunology

Year:

1990

Language:

english

File:

PDF, 391 KB

english, 1990

16

Binding of a major T cell epitope of mycobacteria to a specific pocket within HLA-DRw17(DR3) molecules

Annemieke Geluk, Wim Bloemhoff, René R. P. De Vries, Tom H. M. Ottenhoff

Journal:

European Journal of Immunology

Year:

1992

Language:

english

File:

PDF, 671 KB

english, 1992

17

Mycobacteria induce CD4+ T cells that are cytotoxic and display Th1-like cytokine secretion profile: Heterogeneity in cytotoxic activity and cytokine secretion levels

Tuna Mutis, Yolanthe E. Cornelisse, Tom H. M. Ottenhoff

Journal:

European Journal of Immunology

Year:

1993

Language:

english

File:

PDF, 681 KB

english, 1993

18

T cell receptor and peptide-contacting residues in the HLA-DR17(3) β1 chain

Annemieke Geluk, Xin-Ting Fu, Krista E. van Meijgaarden, Yanourishka Y. R. Jansen, René R. P. de Vries, Robert W. Karr, Tom H. M. Ottenhoff

Journal:

European Journal of Immunology

Year:

1994

Language:

english

File:

PDF, 496 KB

english, 1994

19

Selective stimulation of T helper 2 cytokine responses by the anti-psoriasis agent monomethylfumarate

Rolien de Jong, Anja C. Bezemer, Timo P. L. Zomerdijk, Tineke van de Pouw-Kraan, Tom H. M. Ottenhoff, Peter H. Nibbering

Journal:

European Journal of Immunology

Year:

1996

Language:

english

File:

PDF, 757 KB

english, 1996

20

A DR17-restricted T cell epitope from a secreted Mycobacterium tuberculosis antigen only binds to DR17 molecules at neutral pH

Annemieke Geluk, Krista E. Van Meijgaarden, Rene R. P. De Vries, Alessandro Sette, Tom H. M. Ottenhoff

Journal:

European Journal of Immunology

Year:

1997

Language:

english

File:

PDF, 592 KB

english, 1997

21

IL-12 receptor deficiency revisited: IL-23-mediated signaling is also impaired in human genetic IL-12 receptor β1 deficiency

Marieke A. Hoeve, Tjitske de Boer, Dennis M. L. Langenberg, Ozden Sanal, Frank A. W. Verreck, Tom H. M. Ottenhoff

Journal:

European Journal of Immunology

Year:

2003

Language:

english

File:

PDF, 110 KB

english, 2003

22

Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells

Marieke A. Hoeve, Nigel D. L. Savage, Tjitske de Boer, Dennis M. L. Langenberg, René de Waal Malefyt, Tom H. M. Ottenhoff, Frank A. W. Verreck

Journal:

European Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 341 KB

english, 2006

23

Transcriptional and inflammasome-mediated pathways for the induction of IL-1β production by Mycobacterium tuberculosis

Johanneke Kleinnijenhuis, Leo A. B. Joosten, Frank L. van de Veerdonk, Nigel Savage, Reinout van Crevel, Bart Jan Kullberg, Andre van der Ven, Tom H. M. Ottenhoff, Charles A. Dinarello, Jos W. M. van

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 297 KB

english, 2009

24

Overcoming the global crisis: “Yes, we can”, but also for TB … ?

Tom H. M. Ottenhoff

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 108 KB

english, 2009

25

Double- and monofunctional CD4+ and CD8+ T-cell responses to Mycobacterium tuberculosis DosR antigens and peptides in long-term latently infected individuals

Susanna Commandeur, May Y. Lin, Krista E. van Meijgaarden, Annemieke H. Friggen, Kees L. M. C. Franken, Jan W. Drijfhout, Gro E. Korsvold, Fredrik Oftung, Annemieke Geluk, Tom H. M. Ottenhoff

Journal:

European Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 633 KB

english, 2011

26

Synthesis of Novel Tetrahydropyran-Based Dipeptide Isosters by Overman Rearrangement of 2,3-Didehydroglycosides

Nicole M. A. J. Kriek, Elise van der Hout, Paskal Kelly, Krista E. van Meijgaarden, Annemieke Geluk, Tom H. M. Ottenhoff, Gijs A. van der Marel, Mark Overhand, Jacques H. van Boom, A. Rob P. M. Valent

Journal:

European Journal of Organic Chemistry

Year:

2003

Language:

english

File:

PDF, 193 KB

english, 2003

27

Anti-inflammatory M2 type macrophages characterize metastasized and tyrosine kinase inhibitor-treated gastrointestinal stromal tumors

Minka van Dongen, Nigel D.L. Savage, Ekaterina S. Jordanova, Inge H. Briaire-de Bruijn, Kimberley V. Walburg, Tom H.M. Ottenhoff, Pancras C.W. Hogendoorn, Sjoerd H. van der Burg, Hans Gelderblom, Thor

Journal:

International Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 791 KB

english, 2010

28

Selective modulation of T-cell responses in autoimmunity and cancer

Tom H.M. Ottenhoff

Journal:

Immunology Today

Year:

1996

Language:

english

File:

PDF, 422 KB

english, 1996

29

Mapping the laminin-binding and adhesive domain of the cell surface-associated Hlp/LBP protein from Mycobacterium leprae

Cristiana Soares de Lima, Laurence Zulianello, Maria Ângela de Melo Marques, Heejin Kim, Michelle Iespa Portugal, Sérgio Luiz Antunes, Franco Dante Menozzi, Tom Henricus Maria Ottenhoff, Patrick Josep

Journal:

Microbes and Infection

Year:

2005

Language:

english

File:

PDF, 853 KB

english, 2005

30

The other Janus face of Qa-1 and HLA-E: diverse peptide repertoires in times of stress

Thorbald van Hall, Claudia C. Oliveira, Simone A. Joosten, Tom H.M. Ottenhoff

Journal:

Microbes and Infection

Year:

2010

Language:

english

File:

PDF, 292 KB

english, 2010

31

Host–pathogen interactions

Tom HM Ottenhoff, Michael J Bevan

Journal:

Current Opinion in Immunology

Year:

2004

Language:

english

File:

PDF, 83 KB

english, 2004

32

Introduction: New susceptibility genes in mycobacterial infectious diseases

Tom H.M. Ottenhoff

Journal:

Microbes and Infection

Year:

2006

Language:

english

File:

PDF, 67 KB

english, 2006

33

Human host genetic factors in mycobacterial and Salmonella infection: lessons from single gene disorders in IL-12/IL-23-dependent signaling that affect innate and adaptive immunity

Esther van de Vosse, Tom H.M. Ottenhoff

Journal:

Microbes and Infection

Year:

2006

Language:

english

File:

PDF, 232 KB

english, 2006

34

T cell responses to mycobacterial Ag in HLA-DR3 transgenic mice

Annemieke Geluk, Veena Taneja, Krista van Meijgaarden, René de Vries, Chella David, Tom Ottenhoff

Journal:

Immunology Letters

Year:

1997

Language:

english

File:

PDF, 184 KB

english, 1997

35

Novel human immunodeficiencies reveal the essential role of type-1 cytokines in immunity to intracellular bacteria

Tom H.M Ottenhoff, Dinakantha Kumararatne, Jean-Laurent Casanova

Journal:

Immunology Today

Year:

1998

Language:

english

File:

PDF, 161 KB

english, 1998

36

Human deficiencies in type 1 cytokine receptors reveal the essential role of type 1 cytokines in immunity to intracellular bacteria

Tom H.M Ottenhoff, Tjitske de Boer, Claudia E Verhagen, Frank A.W Verreck, Jaap T van Dissel

Journal:

Microbes and Infection

Year:

2000

Language:

english

File:

PDF, 532 KB

english, 2000

37

Novel mechanisms in the immunopathogenesis of leprosy nerve damage: The role of Schwann cells, T cells and Mycobacterium leprae

Spierings, Eric, De Boer, Tjitske, Zulianello, Laurence, Ottenhoff, Tom HM

Journal:

Immunology & Cell Biology

Year:

2000

Language:

english

File:

PDF, 353 KB

english, 2000

38

Coronin is involved in uptake of Mycobacterium bovis BCG in human macrophages but not in phagosome maintenance

Stephanie Schüller, Jacques Neefjes, Tom Ottenhoff, Jelle Thole, Douglas Young

Journal:

Cellular Microbiology

Year:

2001

Language:

english

File:

PDF, 4.19 MB

english, 2001

39

T-cell and serological responses to Erp, an exportedMycobacterium tuberculosisprotein, in tuberculosis patients and healthy individuals

Valérie Martinez, Guislaine Carcelain, Edgar Badell, Marc Jouan, Isabelle Mauger, Pierre Sellier, Chantal Truffot, François Bricaire, Sandra M Arend, Tom Ottenhoff, Brigitte Autran, Brigitte Gicquel

Journal:

BMC Infectious Diseases

Year:

2007

Language:

english

File:

PDF, 632 KB

english, 2007

40

HLA-DR/DQ Transgenic, class II deficient mice as a novel model to select for HSP T cell epitopes with immunotherapeutic or preventative vaccine potential

Annemieke Geluk, Veena Taneja, Krista E. van Meijgaarden, René R. P. de Vries, Chella S. David, Tom H. M. Ottenhoff

Journal:

Year:

1998

Language:

english

File:

PDF, 443 KB

english, 1998

41

Interleukin–10 promoter haplotypes are differently distributed in the Brazilian versus the Dutch population

Milton O. Moraes, Adalberto R. Santos, Joris J. M. Schonkeren, Patrícia R. Vanderborght, Tom H. M. Ottenhoff, Maria E. Moraes, José R. Moraes, Elizabeth P. Sampaio, Euzenir N. Sarno, Tom W. J. Huizing

Journal:

Year:

2003

Language:

english

File:

PDF, 144 KB

english, 2003

42

Genetic variations in the interleukin-12/interleukin-23 receptor (β1) chain, and implications for IL-12 and IL-23 receptor structure and function

Esther van de Vosse, Elgin G. R. Lichtenauer-Kaligis, Jaap T. van Dissel, Tom H. M. Ottenhoff

Journal:

Year:

2003

Language:

english

File:

PDF, 713 KB

english, 2003

43

Inherited defects in the interferon-gamma receptor or interleukin-12 signalling pathways are not sufficient to cause allergic disease in children

Philip M. D. Wood, Claire Fieschi, Capucine Picard, Tom H. M. Ottenhoff, Jean-Laurent Casanova, Dinakantha S. Kumararatne

Journal:

European Journal of Pediatrics

Year:

2005

Language:

english

File:

PDF, 244 KB

english, 2005

44

Presentation of Interleukin-12/-23 Receptor β1 Deficiency with Various Clinical Symptoms of Salmonella Infections

Ozden Sanal, Tuba Turul, Tijtske De Boer, Esther Van De Vosse, Işik Yalcin, Ilhan Tezcan, Cağman Sun, L. Memis, Tom H. M. Ottenhoff, Fugen Ersoy

Journal:

Journal of Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 335 KB

english, 2006

45

Two Patients with Complete Defects in Interferon Gamma Receptor-Dependent Signaling

Jeroen G. Noordzij, Nico G. Hartwig, Frank A. W. Verreck, Sandra De Bruin-Versteeg, Tjitske De Boer, Jaap T. Van Dissel, Ronald De Groot, Tom H. M. Ottenhoff, Jacques J. M. Van Dongen

Journal:

Journal of Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 279 KB

english, 2007

46

A user-friendly, highly sensitive assay to detect the IFN-γ secretion by T cells

Paul L.A.M. Corstjens, Michel Zuiderwijk, Hans J. Tanke, Jolien J. van der Ploeg-van Schip, Tom H.M. Ottenhoff, Annemiek Geluk

Journal:

Clinical Biochemistry

Year:

2008

Language:

english

File:

PDF, 348 KB

english, 2008

47

Monokine induced by interferon gamma and IFN-γ response to a fusion protein of Mycobacterium tuberculosis ESAT-6 and CFP-10 in Brazilian tuberculosis patients

Clarice Abramo, Krista E. Meijgaarden, Daniely Garcia, Kees L.M.C. Franken, Michèl R. Klein, Arend J. Kolk, Sérgio C. Oliveira, Tom H.M. Ottenhoff, Henrique C. Teixeira

Journal:

Microbes and Infection

Year:

2006

Language:

english

File:

PDF, 279 KB

english, 2006

48

Immunological and functional characterization of Mycobacterium leprae protein antigens: an overview

Jelle E.R. Thole, Brigitte Wieles, Josephine E. Clark-Curtiss, Tom H.M. Ottenhoff, Tobias F. Rinke de Wit

Journal:

Molecular Microbiology

Year:

1995

Language:

english

File:

PDF, 928 KB

english, 1995

49

Unique gene organization of thioredoxin and thioredoxin reductase in Mycobacterium leprae

Brigitte Wieles, Dick van Soolingen, Arne Holmgren, Rienk Offringa, Tom Ottenhoff, Jelle Thole

Journal:

Molecular Microbiology

Year:

1995

Language:

english

File:

PDF, 2.16 MB

english, 1995

50

Mycobacterium leprae-specific protein antigens defined by cloned human helper T cells

Ottenhoff, Tom H. M., Klatser, Paul R., Ivanyi, Juraj, Elferink, Diènne G., de Wit, Madeleine Y. L., de Vries, René R. P.

Journal:

Year:

1986

File:

PDF, 366 KB

1986

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